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Gingival plasma cell granuloma: An enigmatic inflammatory pseudo-tumor with literature review

Gaurav Pandav, Harjit Kaur, Sanjeev Jain, Sakshi Pandav


Plasma cell granulomas (PCGs) also known as inflammatory pseudotumors are tumor like proliferations consisting chiefly of plasma cells, found most commonly in lungs. They can occur in areas such as orbit, head, neck and liver, but rarely they occur in the oral cavity. We here report an exceedingly rare case of gingival PCG in a 52-year-old woman who presented with unusual maxillary gingival overgrowth by excisional biopsy. Histopathological examination of the lesion showed a dense mass consisting of thin keratinized epithelium with proliferating rete ridges. The connective tissue showed hypercellularity. A dense inflammatory infiltrate consisting primarily of plasma cells and lymphocytes was seen in the connective tissue. Focal budding capillaries were seen in the stroma confirming the diagnosis of PCG


Gingival neoplasm; inflammatory pseudotumor; plasma cells; plasma cell granuloma

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