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Search of antilactate dehydrogenase - A molecules - A promising anticancer agent

Masood-ul-Hassan Javed


The aim of this commentary is to summarize some of the recent articles on biology of human lactate dehydrogenase A (hLDH-A) in normal and cancer cells that support the anticancer therapeutic approach based on hLDH-5 inhibition. Up till now, no suitable drug is known that selectively inhibits hLDH-A and can be used for tumor therapies in the clinics throughout the world. This review thus encourages the academic institutions and pharmaceutical industries in search of specifi c inhibitors for hLDH-A


Anticancer agents; human lactate dehydrogenase-A; literature search

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